Dementia is a debilitating condition that affects millions of people worldwide. While the exact causes of dementia are still being studied, research has suggested that certain vitamins and nutrients may play a role in the development and progression of the disease. Two important nutrients to consider are DHA and vitamin B12. In this article, we will explore the relationship between DHA, vitamin B12, and dementia, and how medications such as metformin can impact vitamin levels.
What is DHA?
DHA, or docosahexaenoic acid, is an omega-3 fatty acid that is primarily found in fatty fish and algae. DHA is important for brain function, particularly in the development of neural tissue and the maintenance of cognitive function. Studies have suggested that DHA may help reduce the risk of dementia and cognitive decline in older adults. One study found that higher levels of DHA in the blood were associated with a lower risk of developing dementia. (Source: Alzheimer’s Association – https://www.alz.org/alzheimers-dementia/what-is-dementia)
What is Vitamin B12?
Vitamin B12 is a water-soluble vitamin that is essential for nerve function, DNA synthesis, and red blood cell production. Vitamin B12 is primarily found in animal products, such as meat, dairy, and eggs. Deficiencies in vitamin B12 can lead to anemia, nerve damage, and cognitive impairment. Research has suggested that low levels of vitamin B12 may be associated with an increased risk of dementia and cognitive decline in older adults. (Source: National Institutes of Health – https://ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional/)
The Relationship Between DHA, Vitamin B12, and Dementia
Research has suggested that both DHA and vitamin B12 may play a role in the development and progression of dementia. One study found that older adults with higher levels of DHA in their blood had a lower risk of developing Alzheimer’s disease. Additionally, studies have found that low levels of vitamin B12 may be associated with an increased risk of cognitive decline and dementia. It is important to note, however, that the exact relationship between these nutrients and dementia is still being studied and not fully understood. (Source: Harvard Health Publishing – https://www.health.harvard.edu/alzheimers-and-dementia/omega-3-supplements-and-dementia)
Impact of Medications on Vitamin Levels
Certain medications, such as metformin, can impact vitamin levels in the body. Metformin is a commonly prescribed medication for the treatment of type 2 diabetes. However, studies have found that long-term use of metformin may lead to vitamin B12 deficiencies. This is because metformin can interfere with the absorption of vitamin B12 in the gut. It is important for individuals taking metformin to have their vitamin B12 levels monitored regularly and to consider taking supplements to prevent deficiencies. (Source: Diabetes Care – https://care.diabetesjournals.org/content/34/11/2430)
In conclusion, DHA and vitamin B12 are two important nutrients that may play a role in the development and progression of dementia. Research has suggested that higher levels of DHA and adequate levels of vitamin B12 may help reduce the risk of cognitive decline and dementia in older adults. However, the relationship between these nutrients and dementia is still being studied and not fully understood. Additionally, certain medications, such as metformin, can impact vitamin levels in the body and may lead to deficiencies if not properly monitored. It is important for individuals to speak with their healthcare provider about their nutrient levels and to consider supplementing if deficiencies are present.
If you are someone you know suspects they may have a vitamin or nutrient deficiency read this article on how best to ensure your are getting enough vitamins and minerals for optimal health. Or check out this article instead on Keytones and the key to Dementia
Reach out to find out